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A multivariate pattern analysis of whole-connectome data (MDMR) was used to identify the strongest links between daily cigarette consumption and functional connectivity ( post-hoc testing) involves seed-based analysis of the identified region (see ROI-Based Connectivity Analysis ) to determine the spatial pattern of connectivity it represents ( After preprocessing, resting-state fMRI data were analyzed with MDMR (Figure 1) (Figure 1)

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