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Theoretical mechanism risk The same pathway that supports tissue repair (angiogenesis) also supports tumor growth

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Yu J, Berga SL, Zou W, Taylor RN (2019) Interleukin-1 inhibits estrogen receptor-, progesterone receptors A and B and biomarkers of human endometrial stromal cell differentiation: implications for endometriosis

(2013, Nature Medicine) found that L-carnitine is metabolized by intestinal microbiota to trimethylamine-N-oxide (TMAO), a proatherogenic substance associated with increased CVD risk