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In fact, you may have heard people talk about an Ozempic plateau or a GLP-1 plateau

First Detection of GLP-1 in Arthritic Joint Fluid Earlier studies had suggested GLP-1 might have anti-inflammatory properties, but this marks the first time scientists have detected the hormone directly in the joint fluid of arthritis patients

Resmetirom, the first FDA-approved drug for MASH: from drug discovery and action mechanisms to clinical trials

doi: 10.1016/j.jconrel.2021.05.032, 35

Indeed, the group showed that a GLP-1 infusion directly into the arcuate, and not the paraventricular nucleus, decreased glucose production and glucose uptake by peripheral tissues during clamp studies [93]