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Lantus (Insulin Glargine) Lantus sales in 2022: $2.380 billion (2.259 billion) Company/Developer: Sanofi Date of first FDA approval: April 20, 2000 Indications Lantus is FDA-approved for: Type 1 and 2 diabetes Price of Lantus: $64 to $77 for a 10 mL (100 units/mL) vial and $96 for a pre-filled pen Why it did so well: Touted by Sanofi as the most prescribed long-acting insulin, Lantus was the companys second best-selling drug in 2022