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B12 absorption is regulated through intrinsic factor, which is produced by gastric parietal cells in the stomach, with the B12-intrinsic factor complex being absorbed in the terminal ileum

doi: 10.1038/s41569-019-0202-5 374

Not only that but its estimated that up to 20% of the US population (11) has vitamin B12 deficiency

In the regeneration stage, the fibroblasts (the cells that build the fibers of the connective tissues) proliferate and produce collagens and glycoproteins to form the new tissues

Common observations in clinical settings include transient gastrointestinal effects that typically subside with dose titration