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Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB

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These factors, including lipopolysaccharide (LPS), tumor necrosis factor-alpha (TNF-), and interleukin-1 beta (IL-1), may impede P-gp activity, activate the mitogen-activated protein kinase (MAPK) signaling pathway, and increase nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) expression in ECs

via contaminated drinking water) or overprescribed medication